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Pseudoephedrine and Ibuprofen Suspension and Valdecoxib

Determining the interaction of Pseudoephedrine and Ibuprofen Suspension and Valdecoxib and the possibility of their joint administration.

Check result:

Pseudoephedrine and Ibuprofen Suspension <> Valdecoxib

Relevance: 14.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using ibuprofen together with valdecoxib may lead to increased side effects. This can lead to serious gastrointestinal toxicity including inflammation, bleeding, ulceration, and perforation. The risk is dependent on both dosage and duration of therapy. Talk with your doctor before using these medications together. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Concomitant use of COX-2 inhibitors with other nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the potential for serious gastrointestinal toxicity including inflammation, bleeding, ulceration, and perforation. The risk is dependent on both dosage and duration of therapy.

MANAGEMENT: The use of COX-2 inhibitors with non-aspirin NSAIDs should be avoided. Some authorities consider the use of COX-2 inhibitors with non-aspirin NSAIDs as contraindicated.

References

Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
"Product Information. Celebrex (celecoxib)." Searle, Chicago, IL.
Cerner Multum, Inc. "Australian Product Information." O 0

Pseudoephedrine and Ibuprofen Suspension

Generic Name: ibuprofen / pseudoephedrine

Brand name: Advil Cold & Sinus, Advil Cold and Sinus Liqui-Gel, Dimetapp Sinus, Dristan Sinus, Motrin IB Sinus, Sine-Aid IB, Dayquil Pressure and Pain Caplet, Motrin Cold and Flu, Motrin Childrens Cold, Motrin Sinus Headache, Dimetapp Childrens Cold & Fever, Children's Ibuprofen Cold Relief

Synonyms: Ibuprofen and pseudoephedrine

What is Pseudoephedrine and Ibuprofen Suspension?

Valdecoxib

Generic Name: valdecoxib

Brand name:

Synonyms: Valdecoxib (Oral)

What is Valdecoxib?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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