Pulmicort Spacer and Trelegy Ellipta
Determining the interaction of Pulmicort Spacer and Trelegy Ellipta and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Although they are often combined in clinical practice, the concomitant use of beta-2 adrenergic agonists and corticosteroids may result in additive hypokalemic effects. Since beta-2 agonists can sometimes cause QT interval prolongation, the development of hypokalemia may potentiate the risk of ventricular arrhythmias including torsade de pointes. However, clinical data are limited, and the potential significance is unknown. Patients who are receiving systemic or nebulized formulations of beta-2 agonists, high dosages of inhaled beta-2 agonists, or systemic corticosteroid therapy may be at a greater risk of developing hypokalemia.
- "Product Information. Foradil (formoterol)" Novartis Pharmaceuticals, East Hanover, NJ.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Cerner Multum, Inc. "Australian Product Information." O 0
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
Generic Name: budesonide
Brand name: Entocort EC, Uceris, Pulmicort Flexhaler, Pulmicort Respules
Synonyms: Budesonide, Budesonide (Oral Inhalation)
Generic Name: fluticasone / umeclidinium / vilanterol
Brand name: Trelegy Ellipta
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Pulmicort Spacer-Trelstar
- Pulmicort Spacer-Trelstar Depot
- Pulmicort Spacer-Trelstar LA
- Pulmicort Spacer-Trelstar Mixject
- Pulmicort Spacer-Tremfya
- Pulmicort Spacer-Trental
- Trelegy Ellipta-Pulmicort Turbuhaler
- Trelegy Ellipta-PulmoSal
- Trelegy Ellipta-Pulmozyme
- Trelegy Ellipta-Puralor Ci
- Trelegy Ellipta-PureFe Plus
- Trelegy Ellipta-Purelax