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Pyridoxine and Seconal Sodium

Determining the interaction of Pyridoxine and Seconal Sodium and the possibility of their joint administration.

Check result:

Pyridoxine <> Seconal Sodium

Relevance: 26.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

One small study has suggested that pyridoxine may decrease serum levels of phenobarbital. The mechanism is unknown. Phenobarbital is the only barbiturate specifically implicated in this interaction. However, other barbiturates may behave in a similar fashion. Close observation for altered barbiturate effects is indicated if these drugs must be used together.

References

Hansson O, Sillanpaa M "Pyridoxine and serum concentration of phenytoin and phenobarbitone." Lancet 1 (1976): 256

Pyridoxine

Generic Name: pyridoxine

Brand name: Vitamin B6, Vitelle Nestrex, Pyridoxal 5'-Phosphate

Synonyms: n.a.

What is Pyridoxine?

Seconal Sodium

Generic Name: secobarbital

Brand name: Seconal Sodium, Seconal

Synonyms: n.a.

What is Seconal Sodium?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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