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Pyrimethamine and sulfadoxine and ReVia

Determining the interaction of Pyrimethamine and sulfadoxine and ReVia and the possibility of their joint administration.

Check result:

Pyrimethamine and sulfadoxine <> ReVia

Relevance: 19.10.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using pyrimethamine together with sulfadoxine can increase your risk of anemias. Contact your doctor if you experience any changes in your blood test or if you feel weak or fatigued. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Coadministration of pyrimethamine in doses exceeding 25 mg per week with trimethoprim or sulfonamides may increase the risk of megaloblastic anemia and pancytopenia. The proposed mechanism is additive antifolate effects.

MANAGEMENT: Periodic clinical and laboratory monitoring for signs of folic acid deficiency and hematologic changes is advisable.

References

Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
"Multum Information Services, Inc. Expert Review Panel"

Pyrimethamine and sulfadoxine

Generic Name: pyrimethamine / sulfadoxine

Brand name:

Synonyms: Pyrimethamine and sulfadoxine (Oral)

What is Pyrimethamine and sulfadoxine?

ReVia

Generic Name: naltrexone

Brand name: ReVia, Depade, Vivitrol

Synonyms: Revia

What is ReVia?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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