About us Contacts Drug interactions: 390 212
Drug search by name

Questran Light and Tolazamide

Determining the interaction of Questran Light and Tolazamide and the possibility of their joint administration.

Check result:
Questran Light <> Tolazamide
Relevance: 13.08.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using TOLAZamide together with cholestyramine can alter the effects of TOLAZamide, which can lead to loss of blood sugar control. Talk with your doctor before using TOLAZamide while you are using cholestyramine. TOLAZamide should be administered at least one hour before or four to six hours after cholestyramine. You may need a dose adjustment and you may need to check your blood sugar more often. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Cholestyramine may decrease hypoglycemic effect of some sulfonylureas by decreasing their absorption and enterohepatic recirculation. Data exist for glipizide; the effect of cholestyramine on the pharmacokinetics of other sulfonylureas is unknown.

MANAGEMENT: Sulfonylureas should be administered at least one hour before or four to six hours after cholestyramine. Patients receiving this combination should be advised to closely monitor their blood sugar and to notify their physician if loss of control occurs.

References
  • Kivisto KT, Neuvonen PJ "The effect of cholestyramine and activated charcoal on glipizide absorption." Br J Clin Pharmacol 30 (1990): 733-6
  • "Product Information. Questran (cholestyramine)." Par Pharmaceutical Inc, Chestnut Ridge, NY.
Questran Light

Generic Name: cholestyramine

Brand name: Prevalite, Questran, Questran Light, Cholestyramine Light, Locholest, Locholest Light, Questran Light Packets, Prevalite Packets, Questran Packets

Synonyms: n.a.

Tolazamide

Generic Name: tolazamide

Brand name: Tolinase

Synonyms: TOLAZamide

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction