Quin-G and Rucaparib

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

QuiNIDine may increase the blood levels and effects of rucaparib. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration with potent inhibitors of P-glycoprotein (P-gp) may increase the plasma concentration and the risk of adverse effects of rucaparib, which has been shown to be a substrate of P-gp. However, the effects on the pharmacokinetics of rucaparib have not been evaluated in vivo.

MANAGEMENT: Caution is advised if rucaparib is used concomitantly with potent P-gp inhibitors. Dosage adjustments as well as clinical and laboratory monitoring should be considered whenever a potent P-gp inhibitor is added to or withdrawn from therapy with rucaparib.

Quin-G

Generic Name: quinidine

Brand name: Quin-G, Cardioquin, Quinora, Quinidex Extentabs, Quinaglute Dura-Tabs, Quin-Release

Synonyms: n.a.

What is Quin-G?

Rucaparib

Generic Name: rucaparib

Brand name: Rubraca

Synonyms: n.a.

What is Rucaparib?