Raloxifene Hydrochloride and Xylocaine MPF
Determining the interaction of Raloxifene Hydrochloride and Xylocaine MPF and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Raloxifene is more than 95% protein bound. Caution should be exercised if raloxifene is coadministered with other highly protein-bound drugs. The mechanism is displacement of the drug from its protein-binding site by raloxifene. Displacement may lead to increased free plasma concentrations and potentiate toxicity of drugs affected by raloxifene. Formal in-vitro studies indicate that raloxifene did not affect the binding of warfarin, phenytoin, or tamoxifen. The clinician may want to use caution when raloxifene is used with other highly-protein bound drugs, such as diazepam, diazoxide, or lidocaine.
- "Product Information. Evista (raloxifene)." Lilly, Eli and Company, Indianapolis, IN.
Generic Name: raloxifene
Brand name: Evista
Synonyms: Raloxifene
Generic Name: epinephrine / lidocaine
Brand name: D-Care 100X, Lignospan Forte, Lignospan Standard, Xylocaine MPF With Epinephrine, Xylocaine With Epinephrine
Synonyms: Lidocaine and Epinephrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Raloxifene Hydrochloride-Xylocaine MPF With Epinephrine
- Raloxifene Hydrochloride-Xylocaine Topical application
- Raloxifene Hydrochloride-Xylocaine Topical Solution
- Raloxifene Hydrochloride-Xylocaine With Epinephrine
- Raloxifene Hydrochloride-Xylometazoline
- Raloxifene Hydrochloride-Xylometazoline nasal
- Xylocaine MPF-Raloxifene Hydrochloride Tablets
- Xylocaine MPF-Raltegravir
- Xylocaine MPF-Raltegravir Chewable Tablets
- Xylocaine MPF-Raltegravir Potassium
- Xylocaine MPF-Raltegravir Powder for Oral Suspension
- Xylocaine MPF-Raltegravir Tablets