Rapamune and Welchol (Colesevelam Oral Suspension)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Sirolimus can increase your blood levels of cholesterol and triglycerides. You may need a dose adjustment of colesevelam or more frequent monitoring of your cholesterol levels during treatment with sirolimus. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Higher dosages of lipid-lowering agents may be required during concomitant administration of sirolimus or temsirolimus. Dose-related serum lipid abnormalities, including but not limited to increased serum cholesterol and triglycerides, have been frequently reported in patients treated with sirolimus or temsirolimus.

MANAGEMENT: Close clinical monitoring of serum cholesterol and triglycerides is recommended if sirolimus or temsirolimus is prescribed to patients receiving lipid-lowering agents. Modification of the antihyperlipidemic regimen or dosages may be necessary.

Rapamune

Generic Name: sirolimus

Brand name: Rapamune

Synonyms: n.a.

What is Rapamune?

Welchol (Colesevelam Oral Suspension)

Generic Name: colesevelam

Brand name: Welchol, Colesevelam Hydrochloride

Synonyms: Welchol

What is Welchol (Colesevelam Oral Suspension)?