RE-PB Hyos and Sporanox

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using PHENobarbital together with itraconazole. Using these medications together may decrease the effects of itraconazole. Contact your doctor if your condition or infection worsens. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: The concomitant administration of potent CYP450 3A4 inducers may significantly reduce itraconazole and ketoconazole serum levels. The mechanism appears to be enhanced first-pass metabolism and hepatic enzyme metabolism (CYP450 3A4) of the antifungal agents. Antifungal therapy may fail.

MANAGEMENT: This combination should be avoided. Fluconazole is eliminated unchanged by the kidneys and may be a more appropriate antifungal agent, depending on the patient's condition.

RE-PB Hyos

Generic Name: atropine / hyoscyamine / phenobarbital / scopolamine

Brand name: Donnatal, D-Tal, Phenohytro, Chardonna-2, Hyosophen, Donnapine, Elixiral, Bellatal, Spasmolin, Haponal, Antispas, Barbidonna, Donnatal Extentabs, Antispasmodic, Bellalphen, Donnaphen, Spasquid, Alkabel-SR, Bellatal ER, Servira, PB-Hyos, Quadrapax, Phenobarbital with Belladonna Alkaloids

Synonyms: Belladonna alkaloids and phenobarbital, Hyoscyamine, Atropine, Scopolamine, and Phenobarbital

What is RE-PB Hyos?

Sporanox

Generic Name: itraconazole

Brand name: Sporanox, Onmel, Sporanox PulsePak, Tolsura

Synonyms: n.a.

What is Sporanox?