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Reglan (Metoclopramide Injection Solution) and Sudafed PE Sinus Headache

Determining the interaction of Reglan (Metoclopramide Injection Solution) and Sudafed PE Sinus Headache and the possibility of their joint administration.

Check result:

Reglan (Metoclopramide Injection Solution) <> Sudafed PE Sinus Headache

Relevance: 21.01.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with metoclopramide may enhance the rate and extent of absorption of drugs that are mainly absorbed in the small intestine, such as paracetamol, aspirin, and tetracycline. The proposed mechanism is a metoclopramide-mediated increase in gastric emptying. Clinical and laboratory monitoring should be considered and the dose adjusted as appropriate. The clinical significance of this interaction is unknown.

References

Cerner Multum, Inc. "Australian Product Information." O 0
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Nimmo J, Heading RC, Tothill P, Prescott LF "Pharmacological modification of gastric emptying: effects of propantheline and metoclopramide on paracetamol absorption." Br Med J 1 (1973): 587-9
"Product Information. Reglan (metoclopramide)." Wyeth-Ayerst Laboratories, Philadelphia, PA.

Reglan (Metoclopramide Injection Solution)

Generic Name: metoclopramide

Brand name: Reglan, Metozolv ODT

Synonyms: Reglan

What is Reglan (Metoclopramide Injection Solution)?

Sudafed PE Sinus Headache

Generic Name: acetaminophen / phenylephrine

Brand name: Alka-Seltzer Plus Cold and Sinus, Contac Cold+Flu Non-Drowsy, Excedrin Sinus Headache Caplet, Mapap Sinus Congestion and Pain, QlearQuil Daytime Sinus & Congestion, Robitussin Nasal Relief, Sinus Congestion and Pain Daytime Cool Ice, Sinus Pain & Pressure, Sudafed PE Sinus Headache, Theraflu Daytime Severe Cold, Tylenol Sinus Congestion and Pain, Congespirin Aspirin Free, Neo Citran Extra Strength Cold and Sinus, Mapap Sinus PE, Tylenol Sinus Congestion Daytime, Excedrin Sinus Headache, Non-Pseudo Sinus Pain & Pressure, Robitussin Peak Cold Nasal Relief, Sudafed PE Pressure Plus Pain, Contact Cold and Flu Day, Tylenol Sinus + Headache Day, Vicks Sinex Daytime, Mygrex, Acetaminophen Congestion and Pain, QlearQuil Sinus & Congestion, Vicks DayQuil Sinex

Synonyms: n.a.

What is Sudafed PE Sinus Headache?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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