Retrovir Infusion and Theraflu Severe Cold & Congestion Non-Drowsy
Determining the interaction of Retrovir Infusion and Theraflu Severe Cold & Congestion Non-Drowsy and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Case reports have suggested that the concomitant use of zidovudine and acetaminophen may potentiate the risk of bone marrow suppression and hepatotoxicity; however data have been conflicting. The mechanism is unknown. Until more information is available, patients taking both drugs concurrently should be monitored for the development of hepatotoxicity and bone marrow toxicity.
- Gill PS, Rarick M, Brynes RK, et al "Azidothymidine associated with bone marrow failure in the acquired immunodeficiency syndrome (AIDS)." Ann Intern Med 107 (1987): 502-5
- Sattler FR, Ko R, Antoniskis D, et al "Acetaminophen does not impair clearance of zidovudine." Ann Intern Med 114 (1991): 937-40
- Burger DM, Meenhorst PL, Koks CH, Beijnen JH "Drug interactions with zidovudine." AIDS 7 (1993): 445-60
- Goldsmith JC, Irvine W "Reversible agranulocytosis related to azidothymidine therapy." Am J Hematol 30 (1989): 263-4
- Ameer B "Acetaminophen hepatotoxicity augmented by zidovudine." Am J Med 95 (1993): 342
- Shriner K, Goetz MB "Severe hepatoxicity in a patient receiving both acetaminophen and zidovudine." Am J Med 93 (1992): 94-6
Generic Name: zidovudine
Brand name: Retrovir
Synonyms: Zidovudine (oral/injection), Zidovudine
Generic Name: acetaminophen / dextromethorphan / pseudoephedrine
Brand name: Alka-Seltzer Plus Flu Liquigels, Comtrex Non-Drowsy, Dayquil Liquicaps, Daytime Cold, Non-Drowsy Daytime, Robitussin Honey Flu Non-Drowsy, Theraflu Daytime Severe Cold, Theraflu Severe Cold & Congestion Non-Drowsy, Triaminic Cough & Sore Throat, Triaminic Softchew Throat Pain and Cough, Triaminic Softchews Cough & Sore Throat, EQL Severe Cold, GNP Day Time D Cold/Flu, PX Daytime Multi-Symptom, RA Acetaminophen Flu Cold
Synonyms: Theraflu (pseudoephedrine) Daytime Severe Cold
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Retrovir Infusion-Theraflu Severe Cold & Cough Nighttime
- Retrovir Infusion-Theraflu Severe Cold and Cough
- Retrovir Infusion-Theraflu Severe Cold Nighttime
- Retrovir Infusion-Theraflu Sinus & Cold
- Retrovir Infusion-Theraflu Warming Flu & Sore Throat
- Retrovir Infusion-Theraflu Warming Relief Cold & Chest Congestion
- Theraflu Severe Cold & Congestion Non-Drowsy-Retrovir Intravenous
- Theraflu Severe Cold & Congestion Non-Drowsy-Retrovir oral/injection
- Theraflu Severe Cold & Congestion Non-Drowsy-Revatio
- Theraflu Severe Cold & Congestion Non-Drowsy-Revatio Injection
- Theraflu Severe Cold & Congestion Non-Drowsy-Revatio Intravenous
- Theraflu Severe Cold & Congestion Non-Drowsy-Revefenacin