Retrovir oral/injection and Ritonavir Oral Solution
Determining the interaction of Retrovir oral/injection and Ritonavir Oral Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration of ritonavir (300 mg every six hours) has been reported to decrease the area under the plasma concentration-time curve of zidovudine (200 mg every eight hours) by 25%. The plasma level of ritonavir has been reported not to have been affected. The mechanism of this interaction may be related to the induction of hepatic glucuronosyltransferase activities by ritonavir, which may enhance the glucuronidation of zidovudine. Adjustments in zidovudine dosage are unlikely to be necessary.
- "Product Information. Norvir (ritonavir)." Abbott Pharmaceutical, Abbott Park, IL.
Generic Name: zidovudine
Brand name: Retrovir
Synonyms: Retrovir (oral/injection), Retrovir
Generic Name: ritonavir
Brand name: Norvir, Norvir Soft Gelatin
Synonyms: Ritonavir
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Retrovir oral/injection-Ritonavir Powder Packets
- Retrovir oral/injection-Ritonavir Tablets
- Retrovir oral/injection-Rituxan
- Retrovir oral/injection-Rituxan Hycela
- Retrovir oral/injection-Rituximab
- Retrovir oral/injection-Rituximab and Hyaluronidase
- Ritonavir Oral Solution-Revatio
- Ritonavir Oral Solution-Revatio Injection
- Ritonavir Oral Solution-Revatio Intravenous
- Ritonavir Oral Solution-Revefenacin
- Ritonavir Oral Solution-Revefenacin inhalation
- Ritonavir Oral Solution-Reversol