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Retrovir (Zidovudine Capsules and Tablets) and Zovia 1/35

Determining the interaction of Retrovir (Zidovudine Capsules and Tablets) and Zovia 1/35 and the possibility of their joint administration.

Check result:

Retrovir (Zidovudine Capsules and Tablets) <> Zovia 1/35

Relevance: 09.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Ethinyl estradiol has been shown to inhibit the glucuronidation of zidovudine in vitro. A clinically significant interaction has not been demonstrated, however.

References

Sim SM, Back DJ, Breckenridge AM "The effect of various drugs on the glucuronidation of zidovudine (azidothymidine; AZT) by human liver microsomes." Br J Clin Pharmacol 32 (1991): 17-21

Retrovir (Zidovudine Capsules and Tablets)

Generic Name: zidovudine

Brand name: Retrovir

Synonyms: Retrovir (oral/injection), Retrovir

What is Retrovir (Zidovudine Capsules and Tablets)?

Zovia 1/35

Generic Name: ethinyl estradiol / ethynodiol

Brand name: Kelnor, Zovia 1/35, Zovia 1/50, Demulen 1/35, Demulen 1/50, Zovia 1/35e, Kelnor 1/50, Kelnor 1/35, Zovia 1/50e

Synonyms: Zovia 1/35E

What is Zovia 1/35?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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