Retrovir (Zidovudine Injection) and Valacyclovir Hydrochloride
Determining the interaction of Retrovir (Zidovudine Injection) and Valacyclovir Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Excessive lethargy has been reported in patients receiving concomitant acyclovir and zidovudine. This interaction has not been reported with valacyclovir, but may apply to that drug as well. The mechanism of the interaction is unknown. Dosage reductions may be necessary.
- Stein DS, Graham NM, Park LP, et al. "The effect of the interaction of acyclovir with zidovudine on progression to AIDS and survival. Analysis of data in the Multicenter AIDS cohort study." Ann Intern Med 121 (1994): 100-8
- Bach MC "Possible drug interaction during therapy with azidothymidine and acyclovir for AIDS." N Engl J Med 316 (1987): 547
Generic Name: zidovudine
Brand name: Retrovir
Synonyms: Retrovir (oral/injection), Retrovir
Generic Name: valacyclovir
Brand name: Valtrex
Synonyms: Valacyclovir, ValACYclovir
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Retrovir (Zidovudine Injection)-Valbenazine
- Retrovir (Zidovudine Injection)-Valbenazine Tosylate
- Retrovir (Zidovudine Injection)-Valcyte
- Retrovir (Zidovudine Injection)-Valcyte (Valganciclovir Oral Solution)
- Retrovir (Zidovudine Injection)-Valcyte (Valganciclovir Tablets)
- Retrovir (Zidovudine Injection)-Valdecoxib
- Valacyclovir Hydrochloride-Retrovir (Zidovudine Syrup)
- Valacyclovir Hydrochloride-Retrovir Infusion
- Valacyclovir Hydrochloride-Retrovir Intravenous
- Valacyclovir Hydrochloride-Retrovir oral/injection
- Valacyclovir Hydrochloride-Revatio
- Valacyclovir Hydrochloride-Revatio Injection