Retrovir (Zidovudine Syrup) and Triaminic Softchews Allergy Sinus
Determining the interaction of Retrovir (Zidovudine Syrup) and Triaminic Softchews Allergy Sinus and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Case reports have suggested that the concomitant use of zidovudine and acetaminophen may potentiate the risk of bone marrow suppression and hepatotoxicity; however data have been conflicting. The mechanism is unknown. Until more information is available, patients taking both drugs concurrently should be monitored for the development of hepatotoxicity and bone marrow toxicity.
- Gill PS, Rarick M, Brynes RK, et al "Azidothymidine associated with bone marrow failure in the acquired immunodeficiency syndrome (AIDS)." Ann Intern Med 107 (1987): 502-5
- Sattler FR, Ko R, Antoniskis D, et al "Acetaminophen does not impair clearance of zidovudine." Ann Intern Med 114 (1991): 937-40
- Burger DM, Meenhorst PL, Koks CH, Beijnen JH "Drug interactions with zidovudine." AIDS 7 (1993): 445-60
- Goldsmith JC, Irvine W "Reversible agranulocytosis related to azidothymidine therapy." Am J Hematol 30 (1989): 263-4
- Ameer B "Acetaminophen hepatotoxicity augmented by zidovudine." Am J Med 95 (1993): 342
- Shriner K, Goetz MB "Severe hepatoxicity in a patient receiving both acetaminophen and zidovudine." Am J Med 93 (1992): 94-6
Generic Name: zidovudine
Brand name: Retrovir
Synonyms: Retrovir (oral/injection), Retrovir
Generic Name: acetaminophen / pseudoephedrine
Brand name: Alka-Seltzer Cold and Sinus, Allerest No Drowsiness, Bayer Select Decongestant, Benadryl Allergy Sinus Headache, Dristan Cold Non-Drowsy, Ornex, Ornex Maximum Strength, Sinarest Sinus, Sine-Off Maximum Strength, Tavist Sinus, Triaminic Softchews Allergy Sinus, Bayer Select Sinus Pain Formula, Sudafed Sinus, Contac Sinus, Sinutab Regular Strength, Tylenol Sinus Maximum Strength, Excedrin Sinus, Genapap Sinus, Mapap Sinus, Suphedrin Plus, Phenapap, Pseudoephedrine Sinus, Sinutab Maximum Strength, Sinus Maximum Strength, Tylenol Cold Infants, Suphedrin Sinus, Theraflu Sinus, Sudafed Cold and Sinus, Sudogest Sinus Maximum Strength, Children's Tylenol Sinus, Tylenol Sinus Childrens, Sudafed Sinus Headache, Sinutab Maximum Strength Non Drowsy, Tylenol Sinus Gelcap, Nexafed Sinus Pressure + Pain
Synonyms: Acetaminophen and pseudoephedrine, Acetaminophen and Pseudoephedrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Retrovir (Zidovudine Syrup)-Triaminic Softchews Chest Congestion
- Retrovir (Zidovudine Syrup)-Triaminic Softchews Cough & Sore Throat (pseudoephedrine)
- Retrovir (Zidovudine Syrup)-Triamterene
- Retrovir (Zidovudine Syrup)-Triamterene and hydrochlorothiazide
- Retrovir (Zidovudine Syrup)-Triamterene and Hydrochlorothiazide Capsules
- Retrovir (Zidovudine Syrup)-Triamterene Capsules
- Triaminic Softchews Allergy Sinus-Retrovir Infusion
- Triaminic Softchews Allergy Sinus-Retrovir Intravenous
- Triaminic Softchews Allergy Sinus-Retrovir oral/injection
- Triaminic Softchews Allergy Sinus-Revatio
- Triaminic Softchews Allergy Sinus-Revatio Injection
- Triaminic Softchews Allergy Sinus-Revatio Intravenous