Ribociclib Succinate and Xultophy

• Generic Name: ribociclib
• Dosage Forms: n.a.
• Other Brand Names: Kisqali

Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.

In combination with an aromatase inhibitor for initial treatment of hormone receptor-positive, human epidermal growth factor receptor type 2 (HER2)-negative advanced or metastatic breast cancer in postmenopausal women.

• Generic Name: insulin degludec / liraglutide
• Dosage Forms: injection, solution
• Other Brand Names: Xultophy

Xultophy is an injection pen containing a combination of insulin degludec and liraglutide. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin degludec is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours. Liraglutide is similar to a hormone that occurs naturally in the body and helps control blood sugar, insulin levels, and digestion.

Xultophy is used to lower blood sugar in adults with type 2 diabetes mellitus. This medicine should be used together with diet and exercise.

Xultophy is usually given when your blood sugar levels have not been well controlled by using other medications.

Xultophy is not for people with type 1 diabetes.