Rifadin and Saxagliptin and Metformin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this interaction is not currently available.MONITOR: Coadministration with rifampin may increase the gastrointestinal absorption and therapeutic efficacy of metformin. The mechanism may involve rifampin-mediated induction of the organic cation transporter 1 (OCT1) in the gastrointestinal tract. MANAGEMENT: Until more information is available, caution is advised if rifampin and metformin are used concomitantly. Close clinical monitoring of glycemic control is recommended following initiation or discontinuation of these drugs, and the dosage of metformin may be adjusted as necessary. References Cerner Multum, Inc. "Australian Product Information." O 0 Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

MONITOR: Coadministration with rifampin may increase the gastrointestinal absorption and therapeutic efficacy of metformin. The mechanism may involve rifampin-mediated induction of the organic cation transporter 1 (OCT1) in the gastrointestinal tract.

MANAGEMENT: Until more information is available, caution is advised if rifampin and metformin are used concomitantly. Close clinical monitoring of glycemic control is recommended following initiation or discontinuation of these drugs, and the dosage of metformin may be adjusted as necessary.

Rifadin

Generic Name: rifampin

Brand name: Rifadin, Rifadin IV, Rimactane

Synonyms: n.a.

What is Rifadin?

Saxagliptin and Metformin

Generic Name: metformin / saxagliptin

Brand name: Kombiglyze XR

Synonyms: Metformin and saxagliptin

What is Saxagliptin and Metformin?