Rifadin IV and Super Cold Tabs
Determining the interaction of Rifadin IV and Super Cold Tabs and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Rifampin may slightly decrease the therapeutic effects of acetaminophen, although at usual doses, no intervention appears to be necessary. Additionally, rifampin may increase the risk of hepatotoxicity in patients taking acetaminophen and isoniazid.
- Nolan CM, Sandblom RE, Thummel KE, Slattery JT, Nelson SD "Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis." Chest 105 (1994): 408-11
- Prescott LF, Critchley JA, Balali-Mood M, Pentland B "Effects of microsomal enzyme induction on paracetamol metabolism in man." Br J Clin Pharmacol 12 (1981): 149-53
- Bock KW, Wiltfang J, Blume R, Ullrich D, Bircher J "Paracetamol as a test drug to determine glucuronide formation in man: effects of inducers and of smoking." Eur J Clin Pharmacol 31 (1987): 677-83
Generic Name: rifampin
Brand name: Rifadin IV, Rifadin, Rimactane
Synonyms: n.a.
Generic Name: acetaminophen / chlorpheniramine / phenylephrine
Brand name: Alka-Seltzer Plus Cold, Comtrex Severe Cold & Sinus, Contac Cold+Flu Maximum Strength, Dristan Cold Multi Symptom Formula, Robitussin Nighttime Nasal Relief, Tylenol Allergy Multi-Symptom, Tylenol Children's Plus Cold, Tylenol Sinus Congestion Nighttime, Contac Cold/Flu Day & Night, Coricidin D Cold/Flu/Sinus, Dristan Cold, Medicidin-D, Onset Forte, Robitussin Peak Cold Nasal Relief, Super Cold Tabs, Super Strength Sinadrin, Tylenol Sinus Congestion/Pain, Cold Relief Plus, EQL Effervescent Plus Cold, GNP Cold Relief Plus, QC Cold Relief Plus
Synonyms: Acetaminophen, chlorpheniramine, and phenylephrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Rifadin IV-Super Dent Topical Anesthetic Gel
- Rifadin IV-Super Strength Sinadrin
- Rifadin IV-SuperiorSource K1
- Rifadin IV-Supervite
- Rifadin IV-Suphedrin
- Rifadin IV-Suphedrine
- Super Cold Tabs-Rifadin IV Intravenous
- Super Cold Tabs-Rifamate
- Super Cold Tabs-Rifampin
- Super Cold Tabs-Rifampin and Isoniazid
- Super Cold Tabs-Rifampin Capsules
- Super Cold Tabs-Rifampin Injection