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Rifadin IV and Terbinafine (Systemic)

Determining the interaction of Rifadin IV and Terbinafine (Systemic) and the possibility of their joint administration.

Check result:

Rifadin IV <> Terbinafine (Systemic)

Relevance: 19.01.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Rifampin increases the clearance of terbinafine by 100%. The mechanism probably is hepatic enzyme induction by rifampin. This interaction is unlikely to be of clinical importance; however, the dosage of terbinafine should be adjusted as necessary.

References

"Product Information. Lamisil (terbinafine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.

Rifadin IV

Generic Name: rifampin

Brand name: Rifadin IV, Rifadin, Rimactane

Synonyms: n.a.

What is Rifadin IV?

Terbinafine (Systemic)

Generic Name: terbinafine

Brand name: Lamisil, Terbinex

Synonyms: Terbinafine

What is Terbinafine (Systemic)?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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