About us Contacts Drug interactions: 390 212
Drug search by name

Rifampin Intravenous and Theraflu Nighttime Severe Cold

Determining the interaction of Rifampin Intravenous and Theraflu Nighttime Severe Cold and the possibility of their joint administration.

Check result:
Rifampin Intravenous <> Theraflu Nighttime Severe Cold
Relevance: 15.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Rifampin may slightly decrease the therapeutic effects of acetaminophen, although at usual doses, no intervention appears to be necessary. Additionally, rifampin may increase the risk of hepatotoxicity in patients taking acetaminophen and isoniazid.

References
  • Nolan CM, Sandblom RE, Thummel KE, Slattery JT, Nelson SD "Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis." Chest 105 (1994): 408-11
  • Prescott LF, Critchley JA, Balali-Mood M, Pentland B "Effects of microsomal enzyme induction on paracetamol metabolism in man." Br J Clin Pharmacol 12 (1981): 149-53
  • Bock KW, Wiltfang J, Blume R, Ullrich D, Bircher J "Paracetamol as a test drug to determine glucuronide formation in man: effects of inducers and of smoking." Eur J Clin Pharmacol 31 (1987): 677-83
Rifampin Intravenous

Generic Name: rifampin

Brand name: Rifadin, Rifadin IV, Rimactane

Synonyms: Rifampin

Theraflu Nighttime Severe Cold

Generic Name: acetaminophen / pheniramine / phenylephrine

Brand name: Flu & Severe Cold Night Time, Theraflu Flu & Sore Throat, Theraflu Nighttime Severe Cold, Theraflu Sinus & Cold, Theraflu Cold & Sore Throat, Theraflu Cold and Sore Throat, Theraflu Flu and Sore Throat

Synonyms: Theraflu Flu & Sore Throat

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.