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Riluzole Tablets and Tacrine

Determining the interaction of Riluzole Tablets and Tacrine and the possibility of their joint administration.

Check result:

Riluzole Tablets <> Tacrine

Relevance: 25.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

It is not known if riluzole induces metabolic liver enzymes. Tacrine is metabolized by the same isoenzyme (CYP450 1A2) as riluzole. Theoretically, increased metabolism of tacrine could occur, leading to lower serum concentrations of tacrine. The clinical significance of this interaction is not known. Monitor this patient more closely for altered clinical effect.

References

"Product Information. Rilutek (riluzole)." Rhone-Poulenc Rorer, Collegeville, PA.

Riluzole Tablets

Generic Name: riluzole

Brand name: Rilutek, Tiglutik

Synonyms: Riluzole

What is Riluzole Tablets?

Tacrine

Generic Name: tacrine

Brand name:

Synonyms: Tacrine (Oral)

What is Tacrine?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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