Ritalin SR and Sandimmune Oral
Determining the interaction of Ritalin SR and Sandimmune Oral and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:A case report suggests that methylphenidate may increase the blood concentrations of cyclosporine. The mechanism of interaction and a causal relationship have not been established. In the report, a 10-year-old heart transplant patient developed a significant increase in cyclosporine blood levels shortly after initiation of methylphenidate 5 mg twice a day. The dosage of cyclosporine was subsequently decreased and blood levels returned to therapeutic levels. Methylphenidate was eventually increased to 20 mg twice a day without further incident. Although a drug interaction was suspected by the investigators, patient noncompliance before addition of methylphenidate could not be ruled out.
- Lewis BR, Aoun SL, Bernstein GA, Crow SJ "Pharmacokinetic interactions between cyclosporine and bupropion or methylphenidate." J Child Adolesc Psychopharmacol 11 (2001): 193-8
Generic Name: methylphenidate
Brand name: Methylin ER, Ritalin SR, Adhansia XR, Aptensio XR, Concerta, Cotempla XR-ODT, Jornay PM, Metadate ER, Methylin, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA, Metadate CD, Daytrana
Synonyms: n.a.
Generic Name: cyclosporine
Brand name: Sandimmune, Gengraf, Neoral, Sandimmune
Synonyms: Sandimmune (Injection), Sandimmune
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ritalin SR-Sandostatin
- Ritalin SR-Sandostatin LAR
- Ritalin SR-Sandostatin LAR Depot
- Ritalin SR-Sandostatin LAR Depot injection
- Ritalin SR-Sani-Supp
- Ritalin SR-Sani-Supp rectal
- Sandimmune Oral-Rite Aid First Aid Epsom Salt
- Sandimmune Oral-Rite Aid Night Time Severe Cold and Cough Honey Lemon with Chamomile and White Tea Flavors
- Sandimmune Oral-Rite Aid Senna
- Sandimmune Oral-Ritodrine Oral, Intravenous
- Sandimmune Oral-Ritonavir
- Sandimmune Oral-Ritonavir Capsules