Ropinirole Extended-Release Tablets and Zovia 1/35e

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using ethinyl estradiol together with rOPINIRole may increase the effects of rOPINIRole. This combination may cause nausea, vomiting, weakness, drowsiness, fainting, agitation, and confusion. You may need a dose adjustment if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration with estrogen-containing drugs may increase the plasma concentrations of ropinirole. Data from a population pharmacokinetic study revealed that estrogens, mainly ethinyl estradiol at 0.6 to 3 mg over a 4-month to 23-year period, reduced the oral clearance of ropinirole by up to 36% in 16 patients. The mechanism of interaction has not been described.

MANAGEMENT: Dosage adjustment for ropinirole should not be necessary in patients already on estrogen therapy because patients must be carefully titrated to tolerance or adequate effect. However, if estrogen therapy is initiated or discontinued during treatment with ropinirole, then patients should be monitored for altered ropinirole effects and the dosage adjusted as necessary. Patients should be advised to notify their physician if they experience agitation, orthostasis, sedation, confusion, hallucinations, and/or increased dyskinesia, flushing, dry mouth, sweating, or heart rate.

Ropinirole Extended-Release Tablets

Generic Name: ropinirole

Brand name: Requip, Requip XL, ReQuip Follow on Pack, ReQuip Starter Pack, Repreve, Requip Starter Kit

Synonyms: Ropinirole, ROPINIRole

What is Ropinirole Extended-Release Tablets?

Zovia 1/35e

Generic Name: ethinyl estradiol / ethynodiol

Brand name: Kelnor, Zovia 1/35, Zovia 1/50, Demulen 1/35, Demulen 1/50, Zovia 1/35e, Kelnor 1/50, Kelnor 1/35, Zovia 1/50e

Synonyms: Zovia 1/35, Zovia 1/35E

What is Zovia 1/35e?