Ruxolitinib Phosphate and Simcor

• Generic Name: ruxolitinib
• Dosage Forms: n.a.
• Other Brand Names: Jakafi

Treatment of intermediate- or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential thrombocythemia myelofibrosis (designated an orphan drug by FDA for this use).

• Generic Name: niacin / simvastatin
• Dosage Forms: tablet, film coated, extended release
• Other Brand Names: Simcor

Simcor contains a combination of niacin and simvastatin.

Simcor is used to lower cholesterol and triglycerides (types of fat) in the blood. Simcor is used along with diet to lower levels of total cholesterol, LDL "bad" cholesterol, and triglycerides and to increase HDL "good" cholesterol.

Niacin, also called nicotinic acid, is a B vitamin (vitamin B3). It occurs naturally in plants and animals, and is also added to many foods as a vitamin supplement. Niacin is also present in many multiple vitamins and nutritional supplements.

Simvastatin is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Simvastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).

Simcor may also be used for purposes not listed in this medication guide.