Ruxolitinib Phosphate and Simvastatin and niacin

• Generic Name: ruxolitinib
• Dosage Forms: n.a.
• Other Brand Names: Jakafi

Treatment of intermediate- or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential thrombocythemia myelofibrosis (designated an orphan drug by FDA for this use).

• Generic Name: niacin / simvastatin
• Dosage Forms: n.a.
• Other Brand Names: Simcor

Simvastatin and niacin combination is used together with a proper diet to lower cholesterol and triglyceride (fat) levels in the blood. Simvastatin and niacin may help prevent medical problems caused by clogged blood vessels, such as heart attacks and strokes.

Simvastatin and niacin work together to treat cholesterol and lipid (fat) disorders. Niacin is vitamin B3, which reduces the amount of cholesterol in the blood. Simvastatin belongs to the group of medicines called HMG-CoA inhibitors or statins. It works to reduce the amount of cholesterol in the blood by blocking an enzyme that is needed to make cholesterol.

Simvastatin and niacin was available only with your doctor's prescription. The Simcor(R) product will no longer be marketed in the United States as of April 18, 2016.