Rybix ODT and Skyla

• Generic Name: tramadol
• Dosage Forms: tablet, orally disintegrating
• Other Brand Names: ConZip, Ultram, Ultram ER, Rybix ODT, Ryzolt

Tramadol is used to relieve moderate to moderately severe pain, including pain after surgery. The extended-release capsules or tablets are used for chronic ongoing pain.

Tramadol belongs to the group of medicines called opioid analgesics. It acts in the central nervous system (CNS) to relieve pain.

When tramadol is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

This medicine is available only under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program.

• Generic Name: levonorgestrel
• Dosage Forms: intrauterine device
• Other Brand Names: Skyla, Kyleena, Liletta, Mirena, Aftera, EContra EZ, EContra One-Step, Fallback Solo, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Plan B One-Step, React, Take Action, My Way, Next Choice

Skyla contains levonorgestrel, a female hormone that can cause changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Skyla intrauterine device (IUD) is a small, flexible plastic T-shaped device. This device is placed in the uterus where it slowly releases the hormone to prevent pregnancy for 3 years. (Other types of levonorgestrel intrauterine systems release different amounts of hormone and are used for different lengths of time.)

Skyla can be used whether you have had children or not. It should not be used during pregnancy.

Levonorgestrel is a progestin hormone and does not contain estrogen. The Skyla IUD releases levonorgestrel in the uterus, but only small amounts of the hormone reach the bloodstream. Skyla should not be used as emergency birth control.