Safinamide Mesylate and Sonidegib

• Generic Name: safinamide
• Dosage Forms: n.a.
• Other Brand Names: Xadago

Used as an adjunct to levodopa-carbidopa for the symptomatic treatment of parkinsonian syndrome (e.g., parkinsonism, Parkinson disease [paralysis agitans]) in patients who experience “off” episodes (i.e., time when drug effect wears off and parkinsonian manifestations return).

Shown to be effective only in combination with levodopa-carbidopa; efficacy of safinamide monotherapy not established.

• Generic Name: sonidegib
• Dosage Forms: n.a.
• Other Brand Names: Odomzo

Sonidegib is used to treat basal cell carcinoma (a type of skin cancer).

Sonidegib is usually given when surgery or radiation cannot be used, or have been used without success.

Sonidegib may also be used for purposes not listed in this medication guide.