Sandimmune and Symlin

• Generic Name: cyclosporine
• Dosage Forms: capsule, injection, oral solution
• Other Brand Names: Sandimmune, Gengraf, Neoral, Sandimmune

Cyclosporine injection is given together with a steroid medicine to prevent the body from rejecting a transplanted organ (e.g., kidney, liver, or heart). It belongs to a group of medicines known as immunosuppressive agents.

When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Cyclosporine works by suppressing the immune system to prevent the white blood cells from trying to get rid of the transplanted organ.

Cyclosporine is a very strong medicine. It can cause side effects that can be very serious, such as high blood pressure, kidney problems, or liver problems. It may also decrease the body's ability to fight infections. You and your doctor should talk about the benefits this medicine will do as well as the risks of using it.

This medicine is to be given only by or under the direct supervision of a doctor.

• Generic Name: pramlintide
• Dosage Forms: injection, pen
• Other Brand Names: SymlinPen 120, SymlinPen 60, Symlin

Symlin (pramlintide) is a man-made form of a hormone that occurs naturally in the body. Pramlintide lowers blood sugar in three ways. It slows the rate that food moves from your stomach to your intestines, which keeps your blood sugar from rising too fast. Symlin also lowers the amount of glucose (sugar) your liver produces. Lastly, pramlintide triggers the feeling of fullness after meals to help control your appetite and decrease how much food you eat.

Symlin is used together with insulin to treat type 1 or type 2 diabetes.

Symlin is usually given after other diabetes medicines have been tried without success.