Sandimmune (Cyclosporine Soft Gelatin Capsules) and Terbinafine Tablets
Determining the interaction of Sandimmune (Cyclosporine Soft Gelatin Capsules) and Terbinafine Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Terbinafine may increase the clearance of cyclosporine by up to 15%. The mechanism is unknown. Although this interaction is unlikely to be of clinical importance, it may be appropriate to monitor the patient for decreased cyclosporine efficacy.
- Lo ACY, Lui SL, Lo WK, Chan DTM, Cheng IKP "The interaction of terbinafine and cyclosporine A in renal transplant patients." Br J Clin Pharmacol 43 (1997): 340-1
- "Product Information. Lamisil (terbinafine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
Generic Name: cyclosporine
Brand name: Sandimmune, Gengraf, Neoral, Sandimmune
Synonyms: Sandimmune (Injection), Sandimmune
Generic Name: terbinafine
Brand name: Lamisil, Terbinex
Synonyms: Terbinafine, Terbinafine (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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