Secretin Intravenous and Tisagenlecleucel Intravenous

• Generic Name: secretin
• Dosage Forms: n.a.
• Other Brand Names: ChiRhoStim, SecreFlo

Secretin injection is used for the stimulation of pancreas secretions to help diagnose or find problems in the pancreas and to help identify the ampulla of Vater and accessory papilla during endoscopy. It is also used to help in the diagnosis of gastrinoma (tumor of the bowel or pancreas).

Secretin is to be given only by or under the supervision of a doctor.

• Generic Name: tisagenlecleucel
• Dosage Forms: n.a.
• Other Brand Names: Kymriah

Tisagenlecleucel injection is used to treat B-cell acute lymphoblastic leukemia (ALL) that has come back a second or later time or after other medicines did not work well in patients up to 25 years of age. Leukemia is a type of cancer where the body makes abnormal white blood cells.

Tisagenlecleucel injection is also used to treat diffuse large B-cell lymphoma (DLBCL) that has come back a second or later time or after at least 2 other medicines did not work well. Lymphoma is a type of cancer where the body makes abnormal white blood cells.

Tisagenlecleucel injection is an antineoplastic (cancer) medicine that is made from your own white blood cells. These cells are reprogrammed to contain a chimeric antigen receptor (CAR) to identify the cancer cells from the normal cells and kill them. Before you begin treatment, talk to your doctor about the benefits of tisagenlecleucel as well as the possible risks of receiving it.

Tisagenlecleucel is available only under a restricted distribution program called Kymriah® REMS (Risk Evaluation and Mitigation Strategy) Program.