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Seldane and Tegretol

Determining the interaction of Seldane and Tegretol and the possibility of their joint administration.

Check result:

Seldane <> Tegretol

Relevance: 03.08.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Terfenadine is no longer on the market in the US. Do not take terfenadine with any other medication.

Professional:

MONITOR: A single case report has suggested that coadministration of carbamazepine and terfenadine may elevate free carbamazepine levels and clinical toxicity.

MANAGEMENT: If these drugs must be used together, close monitoring for clinical and laboratory evidence of increased carbamazepine effect is indicated. Patients should be advised to report signs of carbamazepine toxicity (nausea, visual disturbances, dizziness, or ataxia) to their physicians. The carbamazepine dosage may require reduction.

References

Hirschfeld S, Jarosinski P "Drug interaction of terfenadine and carbamazepine." Ann Intern Med 118 (1993): 907-8

Seldane

Generic Name: terfenadine

Brand name: Seldane

Synonyms: n.a.

What is Seldane?

Tegretol

Generic Name: carbamazepine

Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: n.a.

What is Tegretol?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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