Selegiline and Terrell

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Before getting anesthesia with isoflurane, tell your doctor if you are taking selegiline. Using these medications together may significantly affect your blood pressure. In some cases, your doctor may want you to stop taking selegiline for 10 to 14 days before you undergo surgery. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

CONTRAINDICATED: Anecdotal reports have implicated the concomitant use of general anesthesia and nonselective monoamine oxidase inhibitors (MAOIs) as causing hypotension or hypertension. Analysis of these cases suggests that other contributing factors may have been involved (e.g., meperidine and sympathomimetic agents). The safe administration of general anesthetics to patients taking MAOIs has also been reported.

MANAGEMENT: The makers of MAOIs, both selective and nonselective, consider general anesthesia to be contraindicated in patients treated with MAOIs and recommend discontinuing MAOI therapy 10 to 14 days before elective surgery. However, this precaution is generally no longer considered necessary as long as patients are closely monitored during surgery and any adverse or idiosyncratic reactions are promptly managed.

Selegiline

Generic Name: selegiline

Brand name: Eldepryl, Zelapar, Emsam

Synonyms: n.a.

What is Selegiline?

Terrell

Generic Name: isoflurane

Brand name: Forane, Terrell

Synonyms: n.a.

What is Terrell?