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Septra and Vaxchora

Determining the interaction of Septra and Vaxchora and the possibility of their joint administration.

Check result:
Septra <> Vaxchora
Relevance: 14.02.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

If you are currently being treated with sulfamethoxazole or have been treated within the last 14 days, you should talk to your doctor before receiving cholera vaccine, live. Antibiotics like sulfamethoxazole may reduce the activity of the vaccine. To ensure adequate vaccine response, you should not receive cholera vaccine, live until at least 14 days after you complete your sulfamethoxazole therapy. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: The use of live, attenuated cholera vaccine with systemic antibiotics may result in a diminished immunologic response to the vaccine. Some antibiotics may be active against the vaccine strain of Vibrio cholerae, thereby preventing a sufficient degree of multiplication to occur in order to induce a protective immune response.

MANAGEMENT: Live, attenuated cholera vaccine should not be administered during or for at least 14 days after treatment with systemic antibiotics.

References
  • "Product Information. Vaxchora (cholera vaccine, live)." PaxVax, Miami, FL.
Septra

Generic Name: sulfamethoxazole / trimethoprim

Brand name: Septra, Septra DS, Bactrim, Bactrim DS, Bactrim IV, Septra IV, SMZ-TMP DS, Sulfatrim Pediatric, Sulfatrim, Bethaprim, Cotrim, Uroplus, Uroplus DS, Cotrim DS, Bactrim Pediatric, Bethaprim Pediatric, Sulfatrim Suspension, Cotrim Pediatric

Synonyms: n.a.

Vaxchora

Generic Name: cholera vaccine, live

Brand name: Vaxchora

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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