Signifor LAR and Xeomin

• Generic Name: pasireotide
• Dosage Forms: injection
• Other Brand Names: Signifor, Signifor LAR

Signifor LAR is a man-made protein that is similar to a hormone in the body called somatostatin.

Signifor LAR is used to treat Cushing's disease or acromegaly (endocrine disorders). This medicine is usually given after surgery or other treatments did not work or have stopped working.

Signifor LAR may also be used for purposes not listed in this medication guide.

• Generic Name: incobotulinumtoxinA
• Dosage Forms: powder, lyophilized, for solution
• Other Brand Names: Xeomin

Xeomin (incobotulinumtoxinA, also called botulinum toxin type A), is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.

Xeomin injection is used to treat cervical dystonia (severe spasms in the neck muscles), or muscle stiffness in the elbows, wrists, fingers, ankles, or toes.

Xeomin is also used to treat certain eye muscle conditions caused by nerve disorders. This includes uncontrolled blinking or spasm of the eyelids, and a condition in which the eyes do not point in the same direction.

Xeomin is also used to treat chronic drooling (sialorrhea).

Xeomin is also used to temporarily lessen the appearance of facial wrinkles (sometimes called "frown lines") between the eyebrows.