Signifor (Pasireotide Extended-Release Injection) and Tolmetin Sodium

• Generic Name: pasireotide
• Dosage Forms: injection
• Other Brand Names: Signifor, Signifor LAR

• It is used to treat Cushing's disease.
• It is used to treat acromegaly.

• Generic Name: tolmetin
• Dosage Forms: n.a.
• Other Brand Names:

  Tolectin, Tolectin DS, Tolectin 600

Consider potential benefits and risks of tolmetin therapy as well as alternative therapies before initiating therapy with the drug. Use lowest possible effective dosage and shortest duration of therapy consistent with patient's treatment goals.

Symptomatic treatment of osteoarthritis and rheumatoid arthritis.

Management of juvenile rheumatoid arthritis in children ≥2 years of age.

Has been reported to be effective in the management of ankylosing spondylitis (late stages did not respond as well as early stages); has also been used with some success in the treatment of adhesive capsulitis shoulder (frozen shoulder), radiohumeral bursitis (tennis elbow), and local trauma (e.g., recent sprains).