Signifor (Pasireotide Injection) and Vortioxetine Hydrobromide

• Generic Name: pasireotide
• Dosage Forms: injection
• Other Brand Names: Signifor, Signifor LAR

• It is used to treat Cushing's disease.

• Generic Name: vortioxetine
• Dosage Forms: n.a.
• Other Brand Names: Trintellix, Brintellix

Treatment of major depressive disorder in adults.

APA states that effectiveness of antidepressants is generally comparable between and within classes of medications, including SSRIs, SNRIs, tricyclic antidepressants (TCAs), MAO inhibitors, and other antidepressants (e.g., bupropion, mirtazapine, trazodone). Choose antidepressant based mainly on the following factors: patient preference; nature of prior response to medication; safety, tolerability, and anticipated adverse effects; concurrent psychiatric and medical conditions; specific properties of the medication (e.g., half-life, actions on CYP isoenzymes, other drug interactions); and cost. For most patients, an SSRI, SNRI, mirtazapine, or bupropion is considered optimal.