Sirolimus and Torisel

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using sirolimus together with temsirolimus. This can increase the effects of sirolimus. This can cause fever, chills, body aches, fast heart rate, breathing problems, cough, chest tightness, pale skin, easy bruising or bleeding, weakness, or pain or burning when you urinate. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use these medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Coadministration with temsirolimus may potentiate the toxicities of sirolimus. Temsirolimus is metabolized primarily to sirolimus in vivo, thus concomitant administration may result in additive adverse effects, including immunosuppression, renal impairment, and pulmonary toxicity.

MANAGEMENT: Concurrent use of temsirolimus and sirolimus should be avoided.

Sirolimus

Generic Name: sirolimus

Brand name: Rapamune

Synonyms: n.a.

What is Sirolimus?

Torisel

Generic Name: temsirolimus

Brand name: Torisel

Synonyms: n.a.

What is Torisel?