Sitagliptin Phosphate and TheraTears Nutrition

• Generic Name: sitagliptin
• Dosage Forms: n.a.
• Other Brand Names: Januvia

Used as monotherapy as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.

Used in combination with immediate- or extended-release metformin given separately or as a fixed combination (Janumet or Janumet XR, respectively) as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus when treatment with both sitagliptin and metformin is appropriate.

Used in fixed combination with ertugliflozin (Steglujan) as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus when treatment with both drugs is appropriate.

Used in combination with other oral antidiabetic agents (e.g., metformin, a sulfonylurea, a thiazolidinedione [peroxisome proliferator-activated receptor-γ agonist]) or insulin as an adjunct to diet and exercise in patients with type 2 diabetes mellitus who have not achieved adequate glycemic control with one or more oral antidiabetic agents and/or insulin.

American Association of Clinical Endocrinologists/American College of Endocrinology (AACE/ACE) suggests a DPP-4 inhibitor as one of several alternatives for initial monotherapy in patients with metformin contraindications (e.g., renal disease, hepatic disease, GI intolerance, risk of lactic acidosis). DPP-4 inhibitors also recommended as part of combination therapy, particularly with both postprandial and fasting plasma glucose elevations.

Not indicated for use in patients with type 1 diabetes mellitus or diabetic ketoacidosis; insulin is required in these conditions.

• Generic Name: omega-3 polyunsaturated fatty acids
• Dosage Forms: n.a.
• Other Brand Names: Baciguent, Probiotic Formula, Proferrin-ES

TheraTears Nutrition is an oral omega 3 supplement that supports eye comfort and healthy tears. The ingredients in TheraTears Nutrition include fish oil and organic flaxseed oil for their omega 3 content, and vitamin E which acts as an antioxidant.

Essential fatty acids (EFAs) are lipids that cannot be made by our body and have to be obtained from our diet and include fats such as omega 3. EFAs are used by the oil glands in our eyelids to make the oily layer of tear film. TheraTears Nutrition provides omega 3 EFAs that may be used by our oil glands to make good quality tears.

Tear film is made up of three layers – an oil layer, a water layer and a mucin layer (helps the tears to stick to the surface of the eye and provides the underlying cornea with nourishment). Tears are vital for the health of our eye and our vision, without sufficient good quality tears, our eyes are at increased risk for infection and damage from foreign particles. Dry eye is a condition that results from poor quality tears. TheraTears Nutrition is recommended for eye conditions such as dry eye.

TheraTears Nutrition also supports oral health, because the salivary gland and tear glands work in a similar way. The omega 3’s in TheraTears Nutrition help with the production of healthy saliva and help with the maintenance of good oral health.