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Slo-Niacin and Tegretol

Determining the interaction of Slo-Niacin and Tegretol and the possibility of their joint administration.

Check result:
Slo-Niacin <> Tegretol
Relevance: 02.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Case reports suggest that nicotinamide may increase carbamazepine levels. The mechanism may be related to nicotinamide-induced inhibition of carbamazepine metabolism. If these drugs must be used together, close observation for clinical and laboratory evidence of carbamazepine toxicity is recommended.

References
  • Bourgeois BF, Dodson WE, Ferrendellis JA "Interactions between primidone, carbamazepine, and nicotinamide." Neurology 32 (1982): 1122-6
Slo-Niacin

Generic Name: niacin

Brand name: B-3-50, B3-500-Gr, Niacin SR, Niacor, Niaspan ER, Slo-Niacin

Synonyms: n.a.

Tegretol

Generic Name: carbamazepine

Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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