Slow-Mag and Targin

• Generic Name: calcium carbonate / magnesium chloride
• Dosage Forms: n.a.
• Other Brand Names: Mag64, MagDelay, Nu-Mag, Slow-Mag, Magnesium Chloride With Calcium, Slow Magnesium Chloride with Calcium

Calcium and magnesium are naturally occurring minerals. Calcium is needed for bone formation and maintenance. Magnesium helps maintain muscle function and normal heart rhythm.

Slow-Mag is a combination medicine used as a supplement. Slow-Mag is given when your diet does not provide enough of these minerals, or when they are lost through perspiration.

Slow-Mag may also be used for purposes not listed in this medication guide.

• Generic Name: naloxone / oxycodone
• Dosage Forms: n.a.
• Other Brand Names: Targiniq ER

Oxycodone and naloxone combination is used to treat pain severe enough to require daily, around-the-clock, long-term opioid treatment and when other pain medicines did not work well enough or cannot be tolerated.

Oxycodone belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain. Naloxone is used to treat an opioid emergency such as an overdose or a possible overdose of a narcotic medicine.

Oxycodone and naloxone combination should not be used if you need pain medicine for just a short time, such as when recovering from surgery. Do not use this medicine to relieve mild pain, or in situations when non-narcotic medication is effective. This medicine should not be used to treat pain that you only have once in a while or "as needed".

When oxycodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

This medicine is available only under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program.