Sodium Bicarbonate Infant Injection and Solu-MEDROL injection
Determining the interaction of Sodium Bicarbonate Infant Injection and Solu-MEDROL injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Antacids and agents with acid-neutralizing effects may impair the absorption of dexamethasone, prednisolone, prednisone, and other corticosteroids, although data from published studies are somewhat conflicting. The mechanism of interaction and clinical significance are unknown. No particular intervention is necessary during concomitant therapy with these agents, but clinicians should be aware of the potential for interaction.
- Naggar VF, Khalil SA, Gouda MW "Effect of concomitant administration of magnesium trisilicate on GI absorption of dexamethasone in humans." J Pharm Sci 67 (1978): 1029-30
- Tanner AR, Caffin JA, Halliday JW, Powell LW "Concurrent administration of antacids and prednisone: effect on serum levels of prednisolone." Br J Clin Pharmacol 7 (1979): 397-400
- Albin H, Vincon G, Demotes-Mainard F, et al "Effect of aluminium phosphate on the bioavailability of cimetidine and prednisolone." Eur J Clin Pharmacol 26 (1984): 271-3
Generic Name: sodium bicarbonate
Brand name: Neut
Synonyms: Sodium bicarbonate, Sodium Bicarbonate
Generic Name: methylprednisolone
Brand name: A-methapred, Depo-Medrol, Solu-Medrol, Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack
Synonyms: Solu-MEDROL (injection), Solu-Medrol
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Sodium Bicarbonate Infant Injection-SoluCLENZ Rx
- Sodium Bicarbonate Infant Injection-Solurex injection
- Sodium Bicarbonate Infant Injection-Solurex LA injection
- Sodium Bicarbonate Infant Injection-Soma
- Sodium Bicarbonate Infant Injection-Soma Compound
- Sodium Bicarbonate Infant Injection-Soma Compound with Codeine
- Solu-MEDROL injection-Sodium Bicarbonate Injection
- Solu-MEDROL injection-Sodium bicarbonate Oral, Intravenous, Subcutaneous
- Solu-MEDROL injection-Sodium Bicarbonate Tablets
- Solu-MEDROL injection-Sodium Bicarbonate, Citric Acid, and Simethicone Effervescent Granule Pkt
- Solu-MEDROL injection-Sodium biphosphate and sodium phosphate
- Solu-MEDROL injection-Sodium biphosphate and sodium phosphate rectal