Sodium Ferric Gluconate and Tofranil

• Generic Name: sodium ferric gluconate complex
• Dosage Forms: n.a.
• Other Brand Names: Ferrlecit, Nulecit

Treatment of iron deficiency anemia in adult and pediatric hemodialysis patients receiving epoetin alfa therapy.

In patients with chronic kidney disease (CKD) on hemodialysis, IV iron superior to orally administered iron in increasing hemoglobin concentrations and/or minimizing dosage of an erythropoiesis-stimulating agent (ESA) (e.g., epoetin alfa); the National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF-KDOQI) guidelines state that the IV route of iron administration is preferred in such patients.

Limited data suggest that iron sucrose and sodium ferric gluconate injections may be associated less frequently with serious adverse effects (e.g., hypersensitivity reactions) compared with iron dextran injection.

Safety and efficacy not established for the prevention and/or treatment of iron deficiency anemia not associated with CKD (e.g., HIV- or cancer-related anemia).

• Generic Name: imipramine
• Dosage Forms: tablet, sugar coated
• Other Brand Names: Tofranil, Tofranil-PM

Tofranil is a tricyclic antidepressant. This medicine affects chemicals in the brain that may be unbalanced in people with depression.

Tofranil is used to treat symptoms of depression. This medicine is sometimes used to treat bed-wetting in children ages 6 and older.

Tofranil may also be used for purposes not listed in this medication guide.