Sodium oxybate and Zavesca

• Generic Name: sodium oxybate
• Dosage Forms: n.a.
• Other Brand Names: Xyrem

Sodium oxybate is a central nervous system depressant. It is used to treat cataplexy (sudden loss of muscle strength) and reduce daytime sleepiness in patients with narcolepsy.

Sodium oxybate is also known as GHB, a known street drug of abuse. Because of the potential for abuse and serious side effects, sodium oxybate is available only from a certified pharmacy under a special program. Your doctor must be registered in the program in order to prescribe sodium oxybate for you.

Sodium oxybate may also be used for purposes not listed in this medication guide.

• Generic Name: miglustat
• Dosage Forms: capsule
• Other Brand Names: Zavesca

Zavesca (miglustat) reduces the formation of a certain protein in the body in people with type 1 Gaucher disease.

Gaucher disease is a genetic condition in which the body lacks the enzyme needed to break down certain fatty materials (lipids). Lipids can build up in the body, causing symptoms such as easy bruising or bleeding, weakness, anemia, bone or joint pain, enlarged liver or spleen, or weakened bones that are easily fractured.

Zavesca is used to treat mild to moderate type 1 Gaucher disease by people who cannot receive enzyme replacement therapy.

Zavesca may improve the condition of the liver, spleen, bones, and blood cells in people with Type I Gaucher disease. However, it is not a cure for this condition.

Zavesca may also be used for purposes not listed in this medication guide.