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Sodium Sulfate, Potassium Sulfate, and Magnesium Sulfate and Zemplar

Determining the interaction of Sodium Sulfate, Potassium Sulfate, and Magnesium Sulfate and Zemplar and the possibility of their joint administration.

Check result:

Sodium Sulfate, Potassium Sulfate, and Magnesium Sulfate <> Zemplar

Relevance: 08.04.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using paricalcitol together with magnesium sulfate can lead to elevated magnesium blood levels, particularly in individuals with reduced kidney function. Symptoms of high magnesium levels may include nausea, vomiting, flushing, drowsiness, dizziness, confusion, muscle weakness, reduced reflexes, low blood pressure, slow heart rate, and impaired breathing. You should seek medical attention if you experience these symptoms. If you are on dialysis and treated with paricalcitol or other vitamin D medications, you should generally avoid taking products that contain magnesium without first talking to your doctor, as high levels of magnesium over time can lead to bone problems. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Use of magnesium-containing products with a vitamin D analog may increase the risk of hypermagnesemia, particularly in chronic renal dialysis patients, due to potentially additive pharmacologic effects. Chronic hypermagnesemia may have a role in the pathogenesis of adynamic bone disease in dialysis patients.

MANAGEMENT: Patients on chronic renal dialysis treated with a vitamin D analog should avoid magnesium-containing products.

References

"Product Information. Zemplar (paricalcitol)." Abbott Pharmaceutical, Abbott Park, IL.
"Product Information. Hectorol (doxercalciferol)." Genzyme Corporation, Cambridge, MA.
"Product Information. One-Alpha (alfacalcidol)." Pharmel Inc, Montreal, IN.
"Product Information. Rocaltrol (calcitriol)." Roche Laboratories, Nutley, NJ.

Sodium Sulfate, Potassium Sulfate, and Magnesium Sulfate

Generic Name: magnesium sulfate / potassium sulfate / sodium sulfate

Brand name: Suprep Bowel Prep Kit

Synonyms: Magnesium sulfate, potassium sulfate, and sodium sulfate, Sodium Sulfate, Potassium Sulfate, Magnesium Sulfate Oral Solution

What is Sodium Sulfate, Potassium Sulfate, and Magnesium Sulfate?

Zemplar

Generic Name: paricalcitol

Brand name: Zemplar

Synonyms: n.a.

What is Zemplar?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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