Sofosbuvir, velpatasvir, and voxilaprevir and Titralac
Determining the interaction of Sofosbuvir, velpatasvir, and voxilaprevir and Titralac and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Antacids may interfere with the absorption of velpatasvir and reduce its effectiveness. Products with antacid effects typically contain aluminum hydroxide, calcium carbonate, magnesium hydroxide, magnesium carbonate, magnesium oxide, magaldrate, sodium bicarbonate, and/or sodium citrate. To prevent or minimize the interaction, antacid-containing preparations should be taken 4 hours before or 4 hours after the velpatasvir dose. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Concurrent administration of velpatasvir with drugs that elevate gastric pH such as antacids may reduce its gastrointestinal absorption. Velpatasvir exhibits pH-dependent solubility, with increased solubility at lower pH. Drugs that increase gastric pH are expected to decrease the plasma concentration of velpatasvir.
MANAGEMENT: If an antacid is required, the antacid should be taken 4 hours before or 4 hours after administration of sofosbuvir-velpatasvir. The same precaution may be applicable to other drugs with antacid effects.
- "Product Information. Epclusa (sofosbuvir-velpatasvir)." Gilead Sciences, Foster City, CA.
Generic Name: sofosbuvir / velpatasvir / voxilaprevir
Brand name: Vosevi
Synonyms: Sofosbuvir, Velpatasvir, and Voxilaprevir
Generic Name: calcium carbonate
Brand name: Alka-Mints, Alkets, Alkums, Amilac, Amitone, Cal Oys, Cal-Gest, Calcarb, Calci Mix, Calci-Chew, Calcitab, Caltrate, Caltro, Chooz, Dicarbosil, Equilet, Mylanta Child, Nephro Calci, OsCal 500, Oysco 500, Oyst Cal, Oyst Cal 500, Oyster Cal 500, Oyster Calcium, Oyster Shell, Oyster Shell Calcium 500, Rolaids Sodium Free, Super Calcium, Titralac, Tums, Tums 500, Tums E-X, Tums Ultra, Cal-Mint, Calci Mix, Os-Cal 500, Calcium Concentrate, Oyster, Oyster Cal, Calcium Oyster, Calcium Liquid Softgel, Maalox Quick Dissolve, Maalox Quick Dissolve Maximum Strength, Ultra Mylanta Calci Tabs, Extra Strength Mylanta Calci Tabs, Os-Cal, Surpass, Surpass Extra Strength, Icar Prenatal Chewable Calcium, Tums Extra Strength, Maalox Quick Dissolve Extra Strength, Calcium Oyster Shell, Maalox Antacid Barrier, Rolaids Soft Chew, Pepto Children's, Maalox Regular Strength, Maalox Children's, Tums Kids, Tums QuikPak, Calci-Mix, Alcalak, Tums Smoothies, Tums Chewy Bites, Tums Chewy Delights, Tums Sugar-Free
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Sofosbuvir, velpatasvir, and voxilaprevir-Tivicay
- Sofosbuvir, velpatasvir, and voxilaprevir-Tivicay (Dolutegravir 10 mg)
- Sofosbuvir, velpatasvir, and voxilaprevir-Tivicay (Dolutegravir 25 mg and 50 mg)
- Sofosbuvir, velpatasvir, and voxilaprevir-Tivorbex
- Sofosbuvir, velpatasvir, and voxilaprevir-Tizanidine
- Sofosbuvir, velpatasvir, and voxilaprevir-Tizanidine Capsules
- Titralac-Sojourn
- Titralac-Sojourn Inhalant
- Titralac-Solage
- Titralac-Solage Topical
- Titralac-Solaice
- Titralac-Solaice Patch