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Solriamfetol Hydrochloride and Stalevo

Determining the interaction of Solriamfetol Hydrochloride and Stalevo and the possibility of their joint administration.

Check result:
Solriamfetol Hydrochloride <> Stalevo
Relevance: 21.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.MONITOR: Coadministration of solriamfetol with other drugs that increase dopamine levels or that bind directly to dopamine receptors may increase the risk of dopaminergic-related adverse effects. The mechanism of the interaction has not been reported, but it may involve synergistic or additive central dopaminergic effects. This interaction has not been evaluated clinically. MANAGEMENT: Caution is advised if solriamfetol is administered concomitantly with other dopaminergic drugs. Dosage adjustments and close patient monitoring should be considered whenever solriamfetol is used with other dopaminergic drugs. References "Product Information. Sunosi (solriamfetol)." Jazz Pharmaceuticals, Palo Alto, CA.

Professional:

MONITOR: Coadministration of solriamfetol with other drugs that increase dopamine levels or that bind directly to dopamine receptors may increase the risk of dopaminergic-related adverse effects. The mechanism of the interaction has not been reported, but it may involve synergistic or additive central dopaminergic effects. This interaction has not been evaluated clinically.

MANAGEMENT: Caution is advised if solriamfetol is administered concomitantly with other dopaminergic drugs. Dosage adjustments and close patient monitoring should be considered whenever solriamfetol is used with other dopaminergic drugs.

References
  • "Product Information. Sunosi (solriamfetol)." Jazz Pharmaceuticals, Palo Alto, CA.
Solriamfetol Hydrochloride

Generic Name: solriamfetol

Brand name: Sunosi

Synonyms: Solriamfetol

Stalevo

Generic Name: carbidopa / entacapone / levodopa

Brand name: Stalevo, Stalevo 100, Stalevo 125, Stalevo 150, Stalevo 200, Stalevo 50, Stalevo 75

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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