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Solriamfetol Hydrochloride and Tusicof

Determining the interaction of Solriamfetol Hydrochloride and Tusicof and the possibility of their joint administration.

Check result:
Solriamfetol Hydrochloride <> Tusicof
Relevance: 21.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.MONITOR: Additive or synergistic effects on blood pressure and/or heart rate may occur when solriamfetol is combined with other drugs that increase blood pressure and/or heart rate. The use of solriamfetol alone has been associated with dose-dependent increases in blood pressure and heart rate. Combined use of solriamfetol with other drugs that increase blood pressure and/or heart rate has not been studied. MANAGEMENT: Caution is advised if solriamfetol is used with other drugs that increase blood pressure and/or heart rate. Blood pressure should be monitored prior to initiating solriamfetol therapy and regularly during treatment. In addition, hypertension should be controlled prior to treatment, and any new-onset hypertension or exacerbations of pre-existing hypertension that occur during solriamfetol therapy should be treated. Discontinuation of solriamfetol should be considered in patients who experience an increase in blood pressure or heart rate that cannot be managed with dose reduction of solriamfetol or other appropriate medical intervention. References "Product Information. Sunosi (solriamfetol)." Jazz Pharmaceuticals, Palo Alto, CA.

Professional:

MONITOR: Additive or synergistic effects on blood pressure and/or heart rate may occur when solriamfetol is combined with other drugs that increase blood pressure and/or heart rate. The use of solriamfetol alone has been associated with dose-dependent increases in blood pressure and heart rate. Combined use of solriamfetol with other drugs that increase blood pressure and/or heart rate has not been studied.

MANAGEMENT: Caution is advised if solriamfetol is used with other drugs that increase blood pressure and/or heart rate. Blood pressure should be monitored prior to initiating solriamfetol therapy and regularly during treatment. In addition, hypertension should be controlled prior to treatment, and any new-onset hypertension or exacerbations of pre-existing hypertension that occur during solriamfetol therapy should be treated. Discontinuation of solriamfetol should be considered in patients who experience an increase in blood pressure or heart rate that cannot be managed with dose reduction of solriamfetol or other appropriate medical intervention.

References
  • "Product Information. Sunosi (solriamfetol)." Jazz Pharmaceuticals, Palo Alto, CA.
Solriamfetol Hydrochloride

Generic Name: solriamfetol

Brand name: Sunosi

Synonyms: Solriamfetol

Tusicof

Generic Name: dextromethorphan / guaifenesin / phenylephrine

Brand name: Broncotron-D, Duravent DM, Giltuss, Mucinex Fast-Max Severe Congestion & Cough, Phlemex Forte, Robitussin Children's Cough & Cold CF, Robitussin Multi-Symptom Cold, Tusicof, Tussin CF, Vanacof DM, Z-tuss DM, Deconex DMX, Maxiphen DM, Tussex, Tussafed-EX, Sinutuss DM, GDP-EX, Duraphen DM, TriTuss, TriTuss-ER, Tussafed-EX Drops, Certuss-D, Dacex-PE, Anextuss, Dexcon-PE, Zotex LAX, Dacex-DM, Dexcon-DM, Duraphen II DM, Duraphen Forte, G-Phen DM, Despec DM Syrup, Phlemex-PE, Guaphen Forte, Guaphen II DM, Z-Dex, Aquatab C, Robafen CF, DuraMAX, Tusso-XR, Tusso-DM, Robitussin Cough & Cold CF, Ambi 40/1000/60, Maxiphen-G DM, Robitussin Pediatric Cough & Cold CF, Deconex DM, PDM GG, ExeTuss-DM, Endacon DM, Giltuss TR, Q-Tussin CF, Tusso-DMR, Execof ER, Dynatuss EX, Zotex, Robitussin Cough & Cold CF To Go, Zotex-EX, Endacon, Robitussin Cough & Cold CF Max, Mucinex Children's Multi-Symptom Cold, Supress-DX, Tussi-Pres, Tussi-Pres Pediatric, Pres Gen Pediatric, Pres Gen, Robitussin Peak Cold Max Strenth Multi-S, G-Tusicof, Adult Severe Congestion & Cough, Giltuss Pediatrics, Desgen DM, G-Supress DX, Tusslin, Desgen Pediatric, G-Tron Ped, Broncotron Ped, Tusslin Pediatric, Nivanex DMX, Relhist DMX, Giltuss Cough & Cold, Children Giltuss Cough & Cold, VanaTab DM, Tukol Cough & Cold, Robitussin Peak Cold Multi-Sympton Cold, Deconex DMX Poly, Tussidex

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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