Solriamfetol Hydrochloride and Vivelle-Dot

• Generic Name: solriamfetol
• Dosage Forms: n.a.
• Other Brand Names: Sunosi

Solriamfetol hydrochloride is a dopamine and norepinephrine reuptake inhibitor (DNRI) indicated to improve wakefulness in adult patients with excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea (OSA).

Solriamfetol hydrochloride is not indicated to treat the underlying airway obstruction in OSA. Ensure that the underlying airway obstruction is treated (e.g., with continuous positive airway pressure [CPAP]) for at least one month prior to initiating solriamfetol hydrochloride for excessive daytime sleepiness. Modalities to treat the underlying airway obstruction should be continued during treatment with solriamfetol hydrochloride. Solriamfetol hydrochloride is not a substitute for these modalities.

• Generic Name: estradiol
• Dosage Forms: patch, extended release
• Other Brand Names: Alora, Climara, Estradiol Patch, Menostar, Minivelle, Vivelle-Dot, Estraderm, Vivelle, Delestrogen, Depo-Estradiol, Divigel, Elestrin Pump, Estrasorb, EstroGel Pump, Evamist, Estrace, DepoEstradiol, Elestrin, Estradot, Estrogel, Femtrace, Femring, Gynodiol

Estradiol is a form of estrogen, a female sex hormone produced by the ovaries. Estrogen is necessary for many processes in the body.

Vivelle-Dot skin patches are used to treat certain symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. Vivelle-Dot is also used to prevent postmenopausal osteoporosis, or to treat ovarian disorders.

Vivelle-Dot may also be used for purposes not listed in this medication guide.