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Spironolactone and hydrochlorothiazide and Teriparatide

Determining the interaction of Spironolactone and hydrochlorothiazide and Teriparatide and the possibility of their joint administration.

Check result:
Spironolactone and hydrochlorothiazide <> Teriparatide
Relevance: 20.02.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The concomitant administration of hydrochlorothiazide 25 mg and teriparatide did not significantly affect serum calcium response. Urinary excretion of calcium decreased by 15% (clinically insignificant). The effect of higher doses of hydrochlorothiazide is unknown. No action is necessary.

References
  • "Product Information. Forteo (teriparatide)." Lilly, Eli and Company, Indianapolis, IN.
Spironolactone and hydrochlorothiazide

Generic Name: hydrochlorothiazide / spironolactone

Brand name: Aldactazide

Synonyms: Hydrochlorothiazide and spironolactone, Hydrochlorothiazide and Spironolactone

Teriparatide

Generic Name: teriparatide

Brand name: Forteo

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.