Stiripentol Capsules and Tacrolimus Injection
Determining the interaction of Stiripentol Capsules and Tacrolimus Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Stiripentol may increase the blood levels and effects of tacrolimus. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The concomitant administration of stiripentol may increase plasma concentrations and toxic effects of certain hepatically metabolized drugs including ergot alkaloids, quinidine, immunosuppressants, and statins. The mechanism is inhibition of CYP450 3A4 metabolism by stiripentol. Clinical data have not been reported.
MANAGEMENT: The manufacturer recommends that concomitant use should be avoided, unless strictly necessary.
- EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports. Available from: URL: http://www.ema.europa.eu/ema/index.jsp?curl=pages/includes/medicines/medicines_landingpage.jsp&mid."
Generic Name: stiripentol
Brand name: Diacomit
Synonyms: Stiripentol
Generic Name: tacrolimus
Brand name: Astagraf XL, Envarsus XR, Prograf, Hecoria
Synonyms: Tacrolimus (oral and injection), Tacrolimus (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Stiripentol Capsules-Tacrolimus Intravenous
- Stiripentol Capsules-Tacrolimus oral and injection
- Stiripentol Capsules-Tacrolimus Oral, Intravenous
- Stiripentol Capsules-Tactinal
- Stiripentol Capsules-Tadalafil
- Stiripentol Capsules-Tadalafil Tablets (Cialis)
- Tacrolimus Injection-Stiripentol Powder Packets
- Tacrolimus Injection-Stivarga
- Tacrolimus Injection-Stomach Relief - Regular Formula
- Tacrolimus Injection-Stool Softener/Laxative
- Tacrolimus Injection-Strattera
- Tacrolimus Injection-Streptase